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Ccdc3tm1Ish
Targeted Allele Detail
Nomenclature
Symbol: Ccdc3tm1Ish
Name: coiled-coil domain containing 3; targeted mutation 1, Iichiro Shimomura
MGI ID: MGI:5749736
Gene: Ccdc3  Location: Chr2:5137776-5230878 bp, + strand  Genetic Position: Chr2, 3.25 cM, cytoband A1
Decreased epididymal and subcutaneous adipose tissue weight and smaller adiopocyte size in Ccdc3tm1Ish/Ccdc3tm1Ish mice

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:220560
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA genomic region including exon 1 and most of exon 2 was replaced with a floxed neo cassette via homologous recombination. (J:220560)
Generation of the Ccdc3tm1Ish allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccdc3 Mutation:  17 strains or lines available
References
Original:  J:220560 Kobayashi S, et al., Fat/Vessel-derived Secretory Protein (Favine)/CCDC3 Is Involved in Lipid Accumulation. J Biol Chem. 2015 Mar 20;290(12):7443-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory