Prdx3^tm1Hjha
Targeted Allele Detail

Summary

• Symbol: Prdx3^tm1Hjha
• Name: peroxiredoxin 3; targeted mutation 1, Hunjoo Ha
• MGI ID: MGI:5749424
• Synonyms: Prx3 KO, PrxIII⁰
• Gene: Prdx3 Location: Chr19:60852504-60862976 bp, - strand Genetic Position: Chr19, 56.52 cM
• Alliance: Prdx3^tm1Hjha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228860
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An approximately 5.1 kb genomic fragment containing exons 1-4 was replaced with a pgk-neo cassette via homologous recombination. (J:228860)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx3 Mutation: 23 strains or lines available

References

• Original: J:228860 Huh JY, et al., Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression. Antioxid Redox Signal. 2012 Feb 1;16(3):229-43
• All: 6 reference(s)