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Targeted Allele Detail
Symbol: Ubiad1tm1.1Thka
Name: UbiA prenyltransferase domain containing 1; targeted mutation 1.1, Toshio Okano
MGI ID: MGI:5707728
Gene: Ubiad1  Location: Chr4:148518952-148529217 bp, - strand  Genetic Position: Chr4, 78.76 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:221005
Parent Cell Line:  RENKA (ES Cell)
Strain of Origin:  C57BL/6N
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the selection cassette. (J:221005)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ubiad1 Mutation:  22 strains or lines available
Original:  J:221005 Nakagawa K, et al., Vitamin K2 biosynthetic enzyme, UBIAD1 is essential for embryonic development of mice. PLoS One. 2014;9(8):e104078
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.20
The Jackson Laboratory