P2ry14^tm1.1Shbg
Targeted Allele Detail

Summary

• Symbol: P2ry14^tm1.1Shbg
• Name: purinergic receptor P2Y, G-protein coupled, 14; targeted mutation 1.1, Torsten Schoneberg
• MGI ID: MGI:5707037
• Gene: P2ry14 Location: Chr3:59022044-59060913 bp, - strand Genetic Position: Chr3, 28.96 cM
• Alliance: P2ry14^tm1.1Shbg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223427
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: An EMCV-IRES sequence, lacZ gene and floxed neomycin resistance cassette replaced a portion of the coding sequence in exon 3. Cre-mediated recombination removed the selection cassette. (J:223427)

Generation of the P2ry14^tm1.1Shbg allele

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P2ry14 Mutation: 31 strains or lines available

References

• Original: J:223427 Meister J, et al., The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice. J Biol Chem. 2014 Aug 22;289(34):23353-66
• All: 3 reference(s)