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P2ry14tm1.1Shbg
Targeted Allele Detail
Nomenclature
Symbol: P2ry14tm1.1Shbg
Name: purinergic receptor P2Y, G-protein coupled, 14; targeted mutation 1.1, Torsten Schoneberg
MGI ID: MGI:5707037
Gene: P2ry14  Location: Chr3:59114623-59153492 bp, - strand  Genetic Position: Chr3, 28.96 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:223427
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn EMCV-IRES sequence, lacZ gene and floxed neomycin resistance cassette replaced a portion of the coding sequence in exon 3. Cre-mediated recombination removed the selection cassette. (J:223427)
Generation of the P2ry14tm1.1Shbg allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any P2ry14 Mutation:  4 strains or lines available
References
Original:  J:223427 Meister J, et al., The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice. J Biol Chem. 2014 Aug 22;289(34):23353-66
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory