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Olfm2tm1.1Sit
Targeted Allele Detail
Nomenclature
Symbol: Olfm2tm1.1Sit
Name: olfactomedin 2; targeted mutation 1.1, Stanilsav I Tomarev
MGI ID: MGI:5706836
Synonyms: Olfm2-KOLacZ
Gene: Olfm2  Location: Chr9:20667691-20746307 bp, - strand  Genetic Position: Chr9, 7.6 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217902
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2-6 were replaced with a lacZ gene and floxed pgk-neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:217902)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 67 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Olfm2 Mutation:  9 strains or lines available
References
Original:  J:217902 Sultana A, et al., Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice. Exp Neurol. 2014 Nov;261:802-11
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory