Olfm2^tm1.1Sit
Targeted Allele Detail

Summary

• Symbol: Olfm2^tm1.1Sit
• Name: olfactomedin 2; targeted mutation 1.1, Stanilsav I Tomarev
• MGI ID: MGI:5706836
• Synonyms: Olfm2-KO^LacZ
• Gene: Olfm2 Location: Chr9:20578986-20657645 bp, - strand Genetic Position: Chr9, 7.6 cM
• Alliance: Olfm2^tm1.1Sit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217902
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2-6 were replaced with a lacZ gene and floxed pgk-neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:217902)

Expression

In Mice Carrying this Mutation:	67 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olfm2 Mutation: 16 strains or lines available

References

• Original: J:217902 Sultana A, et al., Deletion of olfactomedin 2 induces changes in the AMPA receptor complex and impairs visual, olfactory, and motor functions in mice. Exp Neurol. 2014 Nov;261:802-11
• All: 3 reference(s)