Procrtm1.1(cre/ERT2)Yaz
Targeted Allele Detail
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Symbol: |
Procrtm1.1(cre/ERT2)Yaz |
Name: |
protein C receptor, endothelial; targeted mutation 1.1, Yi Arial Zeng |
MGI ID: |
MGI:5703644 |
Synonyms: |
ProcrCreERT2, ProcrCreERT2-IRES-tdTomato |
Gene: |
Procr Location: Chr2:155593037-155597391 bp, + strand Genetic Position: Chr2, 77.26 cM, cytoband H1-3
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Alliance: |
Procrtm1.1(cre/ERT2)Yaz page
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Germline Transmission: |
Earliest citation of germline transmission:
J:217483
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Parent Cell Line: |
E14TG2a (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Procrtm1.1(cre/ERT2)Yaz expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Procr (MGI:104596) |
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Mutation details: An inducible cre recombinase fusion gene (cre/ERT2), IRES, tdTomato reporter gene and FRT-flanked neomycin resistance cassette were inserted at the translation initiation site. Flp-mediated recombination removed the selection cassette.
(J:217483)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Procr
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Procr Mutation: |
15 strains or lines available
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Original: |
J:217483 Wang D, et al., Identification of multipotent mammary stem cells by protein C receptor expression. Nature. 2015 Jan 1;517(7532):81-4 |
All: |
6 reference(s) |
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