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Targeted Allele Detail
Symbol: Tcimtm1Icle
Name: transcriptional and immune response regulator; targeted mutation 1, Inchul Lee
MGI ID: MGI:5702748
Synonyms: Tc1-
Gene: Tcim  Location: Chr8:24437172-24438946 bp, - strand  Genetic Position: Chr8, 12.47 cM
Germline Transmission:  Earliest citation of germline transmission: J:217318
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA 1373 bp region including the entire gene was replaced with a PGK-neo cassette via homologous recombination. RT-PCR and Western blot analysis confirmed the deletion in homozygous mutant mice. (J:217318)
Generation of the Tcimtm1Icle allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcim Mutation:  0 strains or lines available
Original:  J:217318 Jung Y, et al., TC1(C8orf4) regulates hematopoietic stem/progenitor cells and hematopoiesis. PLoS One. 2014;9(6):e100311
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory