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Tcimtm1Icle
Targeted Allele Detail
Nomenclature
Symbol: Tcimtm1Icle
Name: transcriptional and immune response regulator; targeted mutation 1, Inchul Lee
MGI ID: MGI:5702748
Synonyms: Tc1-
Gene: Tcim  Location: Chr8:24437172-24438946 bp, - strand  Genetic Position: Chr8, 12.47 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217318
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1373 bp region including the entire gene was replaced with a PGK-neo cassette via homologous recombination. RT-PCR and Western blot analysis confirmed the deletion in homozygous mutant mice. (J:217318)
Generation of the Tcimtm1Icle allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcim Mutation:  0 strains or lines available
References
Original:  J:217318 Jung Y, et al., TC1(C8orf4) regulates hematopoietic stem/progenitor cells and hematopoiesis. PLoS One. 2014;9(6):e100311
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory