Sun2^tm1.1Cyh
Targeted Allele Detail

Summary

• Symbol: Sun2^tm1.1Cyh
• Name: Sad1 and UNC84 domain containing 2; targeted mutation 1.1, Ya-Hui Chi
• MGI ID: MGI:5698817
• Gene: Sun2 Location: Chr15:79608271-79626737 bp, - strand Genetic Position: Chr15, 37.85 cM
• Alliance: Sun2^tm1.1Cyh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224769
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted in intron 1, and an FRT-flanked neomycin selection cassette followed by a second loxP site was inserted into intron 4. Exons 2-4 were deleted in ES cells via cre-mediated recombination. (J:224769)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sun2 Mutation: 42 strains or lines available

References

• Original: J:224769 Wang JY, et al., Sun1 deficiency leads to cerebellar ataxia in mice. Dis Model Mech. 2015 Aug 1;8(8):957-67
• All: 1 reference(s)