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Nmt2tm1.1Poru
Targeted Allele Detail
Nomenclature
Symbol: Nmt2tm1.1Poru
Name: N-myristoyltransferase 2; targeted mutation 1.1, Stefan Porubsky
MGI ID: MGI:5696557
Synonyms: Nmt2f
Gene: Nmt2  Location: Chr2:3284212-3328877 bp, + strand  Genetic Position: Chr2, 1.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:226234
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 11. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream from exon 14. Flp-mediated recombination removed the selection cassette and left exons 11 through 14 floxed. (J:226234)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmt2 Mutation:  6 strains or lines available
References
Original:  J:226234 Rampoldi F, et al., Immunosuppression and Aberrant T Cell Development in the Absence of N-Myristoylation. J Immunol. 2015 Nov 1;195(9):4228-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory