About   Help   FAQ
Kcnj11tm1b(EUCOMM)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Kcnj11tm1b(EUCOMM)Wtsi
Name: potassium inwardly rectifying channel, subfamily J, member 11; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5695116
Gene: Kcnj11  Location: Chr7:46097123-46100952 bp, - strand  Genetic Position: Chr7, 29.66 cM
Mutation
origin
Mutant Cell Line:  EPD0974_3_G05
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo
 
Mutation detailsCre-mediated excision of the parental Kcnj11tm1a(EUCOMM)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 33 assay results
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnj11 Mutation:  12 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/07/2020
MGI 6.15
The Jackson Laboratory