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Ddrgk1tm1b(EUCOMM)Hmgu
Targeted Allele Detail
Summary
Symbol: Ddrgk1tm1b(EUCOMM)Hmgu
Name: DDRGK domain containing 1; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:5692746
Gene: Ddrgk1  Location: Chr2:130495955-130506549 bp, - strand  Genetic Position: Chr2, 63.24 cM, cytoband F3
Alliance: Ddrgk1tm1b(EUCOMM)Hmgu page
IMPC: Ddrgk1 gene page
Mutation
origin
Mutant Cell Lines:  HEPD0618_2_D02, HEPD0618_2_D03
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsCre-mediated excision of the parental Ddrgk1tm1a(EUCOMM)Hmgu allele resulted in the removal of the promoter-driven neomycin selection cassette and critical exon 3 and 4 leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 316 assay results
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ddrgk1 Mutation:  20 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory