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Tmem174tm1.1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Tmem174tm1.1(KOMP)Vlcg
Name: transmembrane protein 174; targeted mutation 1.1, Velocigene
MGI ID: MGI:5692686
Gene: Tmem174  Location: Chr13:98771486-98773918 bp, - strand  Genetic Position: Chr13, 52.11 cM, cytoband D1
Alliance: Tmem174tm1.1(KOMP)Vlcg page
IMPC: Tmem174 gene page
Mutation
origin
Mutant Cell Line:  10136A-F11
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsCre-mediated excision of the parental Tmem174tm1(KOMP)Vlcg allele resulted in the removal of the neomycin selection cassette and critical exon(s) leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 24 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tmem174 Mutation:  14 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory