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Sst2C57BL/6J
QTL Variant Detail
Summary
QTL variant: Sst2C57BL/6J
Name: susceptibility to tuberculosis 2; C57BL/6J
MGI ID: MGI:5692305
QTL: Sst2  Location: Chr7:18728794-119485380 bp  Genetic Position: Chr7, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:155722

A genome wide scan in Sst1 resistant (C3H.B6 X C57BL/6J)F2 mice was performed for the purpose of discovering additional loci affecting susceptibility to tuberculosis in mice. Four mouse chromosome regions were identified. Provided here is the chromosome and marker followed by the range , LOD score and resistant allele in parenthesis: Chromosome 7 , Sst2 (D7Mit76 - D7Mit66, LOD = 4.8, C57BL/6J ), Chromosome 12: Sst3 (D12Mit76 - Tel, LOD = 6.6, C3H/HeJ), Chromosome 15 , Sst4 (D15Mit209 - Tel, LOD = 4.6, C57BL/6J ), Chromosome 17 , Sst5 (D17Mit133 - D17Mit87, LOD = 5.5, C57BL/6J ).

References
Original:  J:155722 Yan BS, et al., Genetic architecture of tuberculosis resistance in a mouse model of infection. Genes Immun. 2006 Apr;7(3):201-10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory