Pod^DBA/2J
QTL Variant Detail

Summary

• QTL variant: Pod^DBA/2J
• Name: plasticity of ocular dominance; DBA/2J
• MGI ID: MGI:5692254
• QTL: Pod Location: Chr16:73544845-84350326 bp Genetic Position: Chr16, Syntenic

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:151149

Statistically during monocular deprivation C57BL/6J showed a shift toward the undeprived eye whereas DBA/2J did not allowing for the mapping of the trait in BXD RI lines. Lines 1,2,6,9,11,13,14,16,19,21,27,28,29,31,32,33,34,36,39 and 40 were informativein mapping a QTL for loss of responsiveness after monocular deprivation to mouse chromosome 16 (LRS =21) between rs3656776 (73.63 Mb) and rs3680665 (84.44Mb). Hspa13 (Stch) and Nrip1 were suggested as candidate genes that underlie the QTL.

References

• Original: J:151149 Heimel JA, et al., Genetic control of experience-dependent plasticity in the visual cortex. Genes Brain Behav. 2008 Nov;7(8):915-23
• All: 1 reference(s)