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Abcg1tm1Ched
Targeted Allele Detail
Nomenclature
Symbol: Abcg1tm1Ched
Name: ATP binding cassette subfamily G member 1; targeted mutation 1, Catherine Hedrick
MGI ID: MGI:5691545
Synonyms: Abcg1fl
Gene: Abcg1  Location: Chr17:31276668-31336958 bp, + strand  Genetic Position: Chr17, 15.8 cM, cytoband A2-B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:221785
Parent Cell Line:  iTL IC1 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting vector was designed to have a loxP site upstream of exon 3, and a second loxP site followed by an FRT-flanked neo cassette downstream of exon 3. (J:221785)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Abcg1 Mutation:  35 strains or lines available
References
Original:  J:221785 Sag D, et al., The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun. 2015;6:6354
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory