Abcg1^tm1Ched
Targeted Allele Detail

Summary

• Symbol: Abcg1^tm1Ched
• Name: ATP binding cassette subfamily G member 1; targeted mutation 1, Catherine Hedrick
• MGI ID: MGI:5691545
• Synonyms: Abcg1^fl
• Gene: Abcg1 Location: Chr17:31276668-31336958 bp, + strand Genetic Position: Chr17, 15.8 cM, cytoband A2-B
• Alliance: Abcg1^tm1Ched page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221785
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector was designed to have a loxP site upstream of exon 3, and a second loxP site followed by an FRT-flanked neo cassette downstream of exon 3. (J:221785)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abcg1 Mutation: 45 strains or lines available

References

• Original: J:221785 Sag D, et al., The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity. Nat Commun. 2015;6:6354
• All: 5 reference(s)