About   Help   FAQ
Ctnna1Tvrm5
Chemically induced Allele Detail
Nomenclature
Symbol: Ctnna1Tvrm5
Name: catenin (cadherin associated protein), alpha 1; translational vision research model 5
MGI ID: MGI:5689559
Gene: Ctnna1  Location: Chr18:35118912-35254775 bp, + strand  Genetic Position: Chr18, 18.89 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
    This ENU induced T to C transition results in a leucine to proline mutation at amino acid 436. (J:227177)
Inheritance:    Semidominant
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ctnna1 Mutation:  125 strains or lines available
References
Original:  J:227177 Saksens NT, et al., Mutations in CTNNA1 cause butterfly-shaped pigment dystrophy and perturbed retinal pigment epithelium integrity. Nat Genet. 2015 Dec 21;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/15/2018
MGI 6.12
The Jackson Laboratory