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Maf1em1Lnh
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Maf1em1Lnh
Name: MAF1 homolog, negative regulator of RNA polymerase III; endonuclease-mediated mutation 1, Nouria Hernandez
MGI ID: MGI:5661490
Synonyms: Maf1 +T
Gene: Maf1  Location: Chr15:76235494-76238578 bp, + strand  Genetic Position: Chr15, 35.75 cM, cytoband E1
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Insertion
 
Mutation detailsZinc finger nuclease (ZFN) editing induced a single base pair mutation in the Maf1 gene. The resulting change in reading frame causes a termination of translation after Thr64. (J:222253)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Maf1 Mutation:  9 strains or lines available
References
Original:  J:222253 Bonhoure N, et al., Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev. 2015 May 1;29(9):934-47
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory