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Transgene Detail
Symbol: Tg(HIV-luc)27Tsb
Name: transgene insertion 27, Timothy S Blackwell
MGI ID: MGI:5660354
Synonyms: HLL
Transgene: Tg(HIV-luc)27Tsb  Location: unknown  
Strain of Origin:  Not Specified
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe transgenic construct contains a cDNA encoding firefly luciferase under the control of tandem copies of a 36-base enhancer from the 5' HIV-long terminal repeat (containing two NF-kappaB binding sites, GGGACTTTCC) upstream of a HSV (herpes simplex virus) minimal thymidine kinase promoter. (J:220667)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:220667 Blackwell TS, et al., Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation. Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 1):1095-101
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory