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Gt(ROSA)26Sortm2(CAG-Lancl1)Pfw
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm2(CAG-Lancl1)Pfw
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Paul Worley
MGI ID: MGI:5646274
Synonyms: Rosa26-LanCL1-V5
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077244 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214805
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Gt(ROSA)26Sortm2(CAG-Lancl1)Pfw expresses 1 gene
 
Mutation detailsA CAG promoter, floxed stop cassette and a V5 tagged Lancl1 cDNA were inserted in the locus via homologous recombination. (J:214805)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  497 strains or lines available
References
Original:  J:214805 Huang C, et al., Developmental and activity-dependent expression of LanCL1 confers antioxidant activity required for neuronal survival. Dev Cell. 2014 Aug 25;30(4):479-87
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory