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Targeted Allele Detail
Symbol: Dkk3tm1Tfur
Name: dickkopf WNT signaling pathway inhibitor 3; targeted mutation 1, Takahisa Furukawa
MGI ID: MGI:5645089
Gene: Dkk3  Location: Chr7:111715224-111758264 bp, - strand  Genetic Position: Chr7, 58.74 cM
Germline Transmission:  Earliest citation of germline transmission: J:213794
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 1-3 were replaced with a neo cassette via homologous recombination. (J:213794)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dkk3 Mutation:  21 strains or lines available
Original:  J:213794 Zhu Y, et al., Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging. J Clin Invest. 2014 Jul 1;124(7):3263-73
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.21
The Jackson Laboratory