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Targeted Allele Detail
Symbol: Fgd5tm2Djr
Name: FYVE, RhoGEF and PH domain containing 5; targeted mutation 2, Derrick Rossi
MGI ID: MGI:5642323
Synonyms: Fgd5ZsGr*ZsGr
Gene: Fgd5  Location: Chr6:91978878-92076004 bp, + strand  Genetic Position: Chr6, 41.0 cM
Germline Transmission:  Earliest citation of germline transmission: J:214520
Parent Cell Line:  ART B6-3, B6-3 (ES Cell)
Strain of Origin:  C57BL/6NTac
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsThe targeting vector consists of tandem ZsGreen cassettes separated by a 2A peptide cassette followed by a FRT-flanked neomycin cassette inserted in frame into exon 1. ZsGreen expression is detected in all bone marrow blood vessels in adult mice by laser-scanning cytometry. (J:214520)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgd5 Mutation:  28 strains or lines available
Original:  J:214520 Gazit R, et al., Fgd5 identifies hematopoietic stem cells in the murine bone marrow. J Exp Med. 2014 Jun 30;211(7):1315-31
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory