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Sumo2tm1Weiy
Targeted Allele Detail
Nomenclature
Symbol: Sumo2tm1Weiy
Name: small ubiquitin-like modifier 2; targeted mutation 1, Wei Yang
MGI ID: MGI:5641883
Synonyms: Sumo2-
Gene: Sumo2  Location: Chr11:115413935-115427056 bp, - strand  Genetic Position: Chr11, 80.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217019
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 1 was disrupted by in-frame insertion of two premature stop codons and a neomycin resistance cassette downstream of the ATG codon. Whole-mount in situ hybridization analysis of homozygous mutant embryos confirmed that this is a functionally null allele. (J:217019)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 65 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sumo2 Mutation:  12 strains or lines available
References
Original:  J:217019 Wang L, et al., SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development. EMBO Rep. 2014 Aug;15(8):878-85
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory