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Card11m3Btlr
Chemically induced Allele Detail
Summary
Symbol: Card11m3Btlr
Name: caspase recruitment domain family, member 11; mutation 3, Bruce Beutler
MGI ID: MGI:5640756
Synonyms: hubei
Gene: Card11  Location: Chr5:140858745-140986337 bp, - strand  Genetic Position: Chr5, 79.42 cM
Alliance: Card11m3Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation is an A to G transition at base pair 140,906,767 (v38) on chromosome 5, or base pair 93,830 in the GenBank genomic region NC_000071. The mutation corresponds to residue 863 in the mRNA sequence NM_175362 within exon 5 of 25 total exons. The mutation results in a tyrosine (Y) to cysteine (C) substitution at position 181 (Y181C) (J:221487)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Card11 Mutation:  58 strains or lines available
References
Original:  J:221487 Zeng M, et al., Mutagenetix entry for hubei. MGI Direct Data Submission. 2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory