Lpin2^tm1Reue
Targeted Allele Detail

Summary

• Symbol: Lpin2^tm1Reue
• Name: lipin 2; targeted mutation 1, Karen Reue
• MGI ID: MGI:5640713
• Gene: Lpin2 Location: Chr17:71490527-71556813 bp, + strand Genetic Position: Chr17, 41.87 cM
• Alliance: Lpin2^tm1Reue page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189894
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A beta-geo cassette was inserted into intron 3. Western blot analysis confirmed the absent of protein expression in the liver. (J:189894)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lpin2 Mutation: 57 strains or lines available

References

• Original: J:189894 Dwyer JR, et al., Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2486-95
• All: 2 reference(s)