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Mex3btm1.2Mbld
Targeted Allele Detail
Nomenclature
Symbol: Mex3btm1.2Mbld
Name: mex3 RNA binding family member B; targeted mutation 1.2, Marc Billaud
MGI ID: MGI:5638674
Synonyms: Mex3b-
Gene: Mex3b  Location: Chr7:82867333-82871515 bp, + strand  Genetic Position: Chr7, 47.35 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213588
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was floxed and a floxed neo cassette was inserted via homologous recombination. Cre mediated recombination removed exon 2 and the neo cassette. Molecular analyses confirmed the absence of mRNA and protein in both mouse embryonic fibroblasts (MEFs) and testis extracts from homozygous mutant mice. (J:213588)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mex3b Mutation:  2 strains or lines available
References
Original:  J:213588 Le Borgne M, et al., The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway. Development. 2014 May;141(10):2096-107
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory