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Targeted Allele Detail
Symbol: Camta1tm1.1Eno
Name: calmodulin binding transcription activator 1; targeted mutation 1.1, Eric N Olson
MGI ID: MGI:5637357
Synonyms: CAMTA1fl
Gene: Camta1  Location: Chr4:151059523-151861768 bp, - strand  Genetic Position: Chr4, 81.53 cM
Degeneration of Purkinje cells and cerebellar atrophy in Camta1tm1.1Eno/Camta1tm1.1Eno Tg(Nes-cre)1Kln/0 mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:212232
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 9 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 9 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:212232)
Generation of the Camta1tm1.1Eno and Camta1tm1.2Eno alleles
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Camta1 Mutation:  7 strains or lines available
Original:  J:212232 Long C, et al., Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11521-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory