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Ube2utm1e.1(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Ube2utm1e.1(KOMP)Wtsi
Name: ubiquitin-conjugating enzyme E2U (putative); targeted mutation 1e.1, Wellcome Trust Sanger Institute
MGI ID: MGI:5637184
Gene: Ube2u  Location: Chr4:100478867-100550145 bp, + strand  Genetic Position: Chr4, 45.72 cM
Mutation
origin
Mutant Cell Line:  EPD0036_4_F06
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt0
 
Mutation detailsCre-mediated excision of the parental Ube2utm1e(KOMP)Wtsi allele resulted in the removal of the promoter-driven neomycin selection cassette leaving behind the inserted lacZ reporter sequence. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:204739)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ube2u Mutation:  25 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory