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Tnfrsf11atm1.1Irw
Targeted Allele Detail
Nomenclature
Symbol: Tnfrsf11atm1.1Irw
Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator; targeted mutation 1.1, Ifor R Williams
MGI ID: MGI:5629957
Synonyms: RANKF, RANKFL
Gene: Tnfrsf11a  Location: Chr1:105708443-105775709 bp, + strand  Genetic Position: Chr1, 49.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:219915
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsExons 2 and 3 were floxed. Flp-mediated recombination removed the FRT-flanked selection cassette inserted upstream of exon 2. (J:219915)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnfrsf11a Mutation:  26 strains or lines available
References
Original:  J:219915 Powell JJ, et al., An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells. Nat Nanotechnol. 2015 May;10(4):361-9
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/16/2021
MGI 6.17
The Jackson Laboratory