About   Help   FAQ
Mapk9tm2.1Rjd
Targeted Allele Detail
Nomenclature
Symbol: Mapk9tm2.1Rjd
Name: mitogen-activated protein kinase 9; targeted mutation 2.1, Roger J Davis
MGI ID: MGI:5629588
Synonyms: Jnk2LoxP
Gene: Mapk9  Location: Chr11:49846751-49886421 bp, + strand  Genetic Position: Chr11, 29.96 cM, cytoband B1.2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:192551
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA floxed neomycin resistance cassette was inserted upstream of exon 6. An additional loxP site was inserted downstream of exon 7 alpha. Cre-mediated recombination removed the selection cassette and left exons 6, 7beta and 7alpha floxed. (J:192551)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk9 Mutation:  8 strains or lines available
References
Original:  J:192551 Han MS, et al., JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science. 2013 Jan 11;339(6116):218-22
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/24/2020
MGI 6.15
The Jackson Laboratory