Olig1^tm1Wdr
Targeted Allele Detail

Summary

• Symbol: Olig1^tm1Wdr
• Name: oligodendrocyte transcription factor 1; targeted mutation 1, William D Richardson
• MGI ID: MGI:5629414
• Gene: Olig1 Location: Chr16:91066660-91068821 bp, + strand Genetic Position: Chr16, 52.67 cM
• Alliance: Olig1^tm1Wdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210099
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence was replaced with a floxed neomycin resistance cassette and Notch1 intracellular domain (NICD) that is not expressed. (J:210099)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Olig1 Mutation: 13 strains or lines available

References

• Original: J:210099 Paes de Faria J, et al., New Olig1 null mice confirm a non-essential role for Olig1 in oligodendrocyte development. BMC Neurosci. 2014;15:12
• All: 1 reference(s)