Lhx9tm1.1(cre/ERT2)Gan
Targeted Allele Detail
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Symbol: |
Lhx9tm1.1(cre/ERT2)Gan |
Name: |
LIM homeobox protein 9; targeted mutation 1.1, Lin Gan |
MGI ID: |
MGI:5620763 |
Synonyms: |
Lhx9GCE, Lhx9-GFPCreERT2, Lhx9tm1.1(EGFP/cre/ERT2)Gan |
Gene: |
Lhx9 Location: Chr1:138752924-138776315 bp, - strand Genetic Position: Chr1, 60.82 cM, cytoband G-H2
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Alliance: |
Lhx9tm1.1(cre/ERT2)Gan page
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Small body size of Lhx9tm1.1(cre/ERT2)Gan/Lhx9tm1.1(cre/ERT2)Gan mice
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:214080
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6J x 129S6/SvEvTac
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Lhx9tm1.1(cre/ERT2)Gan expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting construct replaced exon 4 with an EGFP, inducible cre recombinase fusion gene (EGFP/cre/ERT2) and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. The EGFP could not be detected by direct fluorescence or anti-GFP antibody staining. Expression of the EGFP/cre/ERT2 fusion protein is detected by anti-estrogen receptor antibody staining in adult retinal neurons.
(J:214080)
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Generation of the Lhx9tm1.1(cre/ERT2)Gan allele |
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Lhx9
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lhx9 Mutation: |
31 strains or lines available
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Original: |
J:214080 Balasubramanian R, et al., Generation and characterization of Lhx9-GFPCreER(T2) knock-in mouse line. Genesis. 2014 Sep;52(9):827-32 |
All: |
1 reference(s) |
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