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Lhx9tm1.1(cre/ERT2)Gan
Targeted Allele Detail
Summary
Symbol: Lhx9tm1.1(cre/ERT2)Gan
Name: LIM homeobox protein 9; targeted mutation 1.1, Lin Gan
MGI ID: MGI:5620763
Synonyms: Lhx9GCE, Lhx9-GFPCreERT2, Lhx9tm1.1(EGFP/cre/ERT2)Gan
Gene: Lhx9  Location: Chr1:138752924-138776315 bp, - strand  Genetic Position: Chr1, 60.82 cM, cytoband G-H2
Alliance: Lhx9tm1.1(cre/ERT2)Gan page
Small body size of Lhx9tm1.1(cre/ERT2)Gan/Lhx9tm1.1(cre/ERT2)Gan mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214080
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J x 129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Lhx9tm1.1(cre/ERT2)Gan expression driven by 1 gene
 
Mutation detailsThe targeting construct replaced exon 4 with an EGFP, inducible cre recombinase fusion gene (EGFP/cre/ERT2) and an FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. The EGFP could not be detected by direct fluorescence or anti-GFP antibody staining. Expression of the EGFP/cre/ERT2 fusion protein is detected by anti-estrogen receptor antibody staining in adult retinal neurons. (J:214080)
Generation of the Lhx9tm1.1(cre/ERT2)Gan allele
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lhx9 (mouse)
Summary of all recombinase alleles driven by Lhx9.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx9 Mutation:  31 strains or lines available
References
Original:  J:214080 Balasubramanian R, et al., Generation and characterization of Lhx9-GFPCreER(T2) knock-in mouse line. Genesis. 2014 Sep;52(9):827-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory