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Myl1tm1.1(cre/ERT2)Lepr
Targeted Allele Detail
Nomenclature
Symbol: Myl1tm1.1(cre/ERT2)Lepr
Name: myosin, light polypeptide 1; targeted mutation 1.1, Christoph Lepper
MGI ID: MGI:5620012
Synonyms: Myl1CE
Gene: Myl1  Location: Chr1:66924295-66945404 bp, - strand  Genetic Position: Chr1, 33.71 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:210509
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6 x 129
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA rabbit beta-globin intron, cre/ERT2 fusion gene, SV40 late polyadenylation signal and FRT-flanked neomycin cassette replaced the coding sequence in exon 1. Flp-mediated recombination removed the selection cassette. (J:210509)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myl1     Summary of all recombinase alleles driven by Myl1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myl1 Mutation:  5 strains or lines available
References
Original:  J:210509 Southard S, et al., A series of Cre-ER drivers for manipulation of the skeletal muscle lineage. Genesis. 2014 May 21;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/17/2017
MGI 6.10
The Jackson Laboratory