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H2-Ab1em1Ygch
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: H2-Ab1em1Ygch
Name: histocompatibility 2, class II antigen A, beta 1; endonuclease-mediated mutation 1, Yi-Guang Chen
MGI ID: MGI:5618308
Synonyms: H2-Ab- line 11
Gene: H2-Ab1  Location: Chr17:34482201-34488392 bp, + strand  Genetic Position: Chr17, 17.98 cM
Mutation
origin
Strain of Origin:  NOD/ShiLtJ
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsZinc-finger nuclease technology generated a 17 bp deletion in exon 2 that disrupts normal expression of this diabetes susceptibility allele. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any H2-Ab1 Mutation:  70 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory