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Pomgnt2tm1Kkat
Targeted Allele Detail
Nomenclature
Symbol: Pomgnt2tm1Kkat
Name: protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2; targeted mutartion 1, Koichi Kato
MGI ID: MGI:5617746
Synonyms: AGO61-KO
Gene: Pomgnt2  Location: Chr9:121810672-121825116 bp, - strand  Genetic Position: Chr9, 72.78 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215959
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    The first coding exon was replaced with a neomycin resistance cassette. (J:215959)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 14 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pomgnt2 Mutation:  23 strains or lines available
Notes
ES cell line = TT2 or HK3i. This allele was made in either TT2 ES cells, derived from a (C57BL/6NCrlj x CBA/JNCrlj)F1 embryo, or in HK3i ES cells, derived from C57BL/6NJcl. Alternatively, both cell lines may have been used. (J:215959; LARGE, RIKEN Center for Life Science Technologies)
References
Original:  J:215959 Yagi H, et al., AGO61-dependent GlcNAc modification primes the formation of functional glycans on alpha-dystroglycan. Sci Rep. 2013;3:3288
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2022
MGI 6.21
The Jackson Laboratory