Cdh5^tm5Dvst
Targeted Allele Detail

Summary

• Symbol: Cdh5^tm5Dvst
• Name: cadherin 5; targeted mutation 5, Dietmar Vestweber
• MGI ID: MGI:5617005
• Synonyms: VEC-Y685F
• Gene: Cdh5 Location: Chr8:104828257-104871143 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Cdh5^tm5Dvst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209801
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (RMCE-ready)
• Mutations: Insertion, Nucleotide substitutions

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdh5 Mutation: 53 strains or lines available

Notes

This allele was generated from Cdh5^tm1Dvst.

References

• Original: J:209801 Wessel F, et al., Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin. Nat Immunol. 2014 Mar;15(3):223-30
• All: 3 reference(s)