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Rpgrtm1.1Sgj
Targeted Allele Detail
Nomenclature
Symbol: Rpgrtm1.1Sgj
Name: retinitis pigmentosa GTPase regulator; targeted mutation 1.1, Samuel G Jacobson
MGI ID: MGI:5610131
Gene: Rpgr  Location: ChrX:10158216-10216795 bp, - strand  Genetic Position: ChrX, 4.62 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213970
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site inserted upstream of exon 1. A floxed neomycin resistance cassette inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the selection cassette. (J:213970)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rpgr Mutation:  2 strains or lines available
References
Original:  J:213970 Huang WC, et al., RPGR-associated retinal degeneration in human X-linked RP and a murine model. Invest Ophthalmol Vis Sci. 2012;53(9):5594-608
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory