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Mars2tm1.1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Mars2tm1.1(KOMP)Vlcg
Name: methionine-tRNA synthetase 2 (mitochondrial); targeted mutation 1.1, Velocigene
MGI ID: MGI:5608699
Gene: Mars2  Location: Chr1:55276336-55279217 bp, + strand  Genetic Position: Chr1, 28.08 cM
Alliance: Mars2tm1.1(KOMP)Vlcg page
IMPC: Mars2 gene page
Mutation
origin
Mutant Cell Line:  11264A-D2
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1777bp between positions 55294070-55295846 of Chromosome 1 (Genome Build37) and subsequent Cre-mediated excision deleted the neomycin selection cassette. (J:136110, J:188991)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 59 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mars2 Mutation:  13 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory