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Fastm1.1(ALPP)Chnd
Targeted Allele Detail
Nomenclature
Symbol: Fastm1.1(ALPP)Chnd
Name: Fas (TNF receptor superfamily member 6); targeted mutation 1.1, Christopher Henderson
MGI ID: MGI:5607749
Gene: Fas  Location: Chr19:34290666-34327772 bp, + strand  Genetic Position: Chr19, 29.48 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J/J
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsUsing a BAC-based targeting approach, a loxP-splice acceptor (SA) site was introduced to intron 1 of the Fas gene and an FRT-PGK-Neo-FRT-loxP-SA-human placental alkaline phosphatase (PLAP)-pA was placed in intron 9. Flp-mediated recombination removed the neomycin cassette. (J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fas Mutation:  53 strains or lines available
Notes
ES cell line = CSL2J2
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory