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Cers6tm1Arte
Targeted Allele Detail
Nomenclature
Symbol: Cers6tm1Arte
Name: ceramide synthase 6; targeted mutation 1, TaconicArtemis
MGI ID: MGI:5607416
Synonyms: CerS6loxP
Gene: Cers6  Location: Chr2:68861441-69114282 bp, + strand  Genetic Position: Chr2, 39.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215519
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exon 4 was flanked by loxP sites. (J:215519)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cers6 Mutation:  29 strains or lines available
References
Original:  J:215519 Turpin SM, et al., Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metab. 2014 Oct 7;20(4):678-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory