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Zfp318tm1.1Jhws
Targeted Allele Detail
Nomenclature
Symbol: Zfp318tm1.1Jhws
Name: zinc finger protein 318; targeted mutation 1.1, John Weis
MGI ID: MGI:5606279
Synonyms: Zfp318Fl
Gene: Zfp318  Location: Chr17:46694657-46731846 bp, + strand  Genetic Position: Chr17, 22.9 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215815
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe targeting vector was designed to insert a loxP site upstream of the promoter, and a frt-flanked neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 2 of the gene. FLP mediated recombination removed the FRT-flanked neo cassette. (J:215815)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Zfp318 Mutation:  47 strains or lines available
References
Original:  J:215815 Pioli PD, et al., Zfp318 regulates IgD expression by abrogating transcription termination within the Ighm/Ighd locus. J Immunol. 2014 Sep 1;193(5):2546-53
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory