Tg(IKBKAP*)#Sasl
Transgene Detail

Summary

• Symbol: Tg(IKBKAP*)#Sasl
• Name: transgene insertion, Susan Slaugenkaupt
• MGI ID: MGI:5602879
• Transgene: Tg(IKBKAP*)#Sasl Location: unknown
• Alliance: Tg(IKBKAP*)#Sasl page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(IKBKAP*)#Sasl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ELP1 (8518)

  Elp1	(MGI:1914544)

• Mutation details: A T to C change was created in position 6 of intron 20 of IKBKAP in human BAC clone RP11-234B17 which also contains part of CTNNAL1, C9orf6, ACTL7A, and ACTL7B waa inserted. (J:145261)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:145261 Hims MM, et al., A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. Genomics. 2007 Sep;90(3):389-96
• All: 5 reference(s)