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Tshz1tm2.1Garr
Targeted Allele Detail
Nomenclature
Symbol: Tshz1tm2.1Garr
Name: teashirt zinc finger family member 1; targeted mutation 2.1, Alistair N Garratt
MGI ID: MGI:5588816
Synonyms: Tshz1flox
Gene: Tshz1  Location: Chr18:84011627-84086562 bp, - strand  Genetic Position: Chr18, 57.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:209428
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site and a single frt site were inserted into intron upstream of exon2, and another loxP site was inserted into intron downstream of exon2 of Tshz1 gene. This allele was generated by crossing Tshz1tm2Garr chimera mice with mice carrying the Flp-e deleter allele Tg(ACTFLPe)9205Dym to remove neo-cassette. (J:209428)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tshz1 Mutation:  0 strains or lines available
References
Original:  J:209428 Ragancokova D, et al., TSHZ1-dependent gene regulation is essential for olfactory bulb development and olfaction. J Clin Invest. 2014 Mar 3;124(3):1214-27
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory