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Uts2tm1Ags
Targeted Allele Detail
Nomenclature
Symbol: Uts2tm1Ags
Name: urotensin 2; targeted mutation 1, Adel Giaid Schwertani
MGI ID: MGI:5588699
Synonyms: UII KO
Gene: Uts2  Location: Chr4:150997097-151001810 bp, + strand  Genetic Position: Chr4, 81.53 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:214289
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA targeting vector containing an IRES sequence, lacZ and a Pgk-NEO cassette was used to disrupt half of exon 4 and all of exons 5 and 6. (J:214289)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Uts2 Mutation:  12 strains or lines available
References
Original:  J:214289 Kiss RS, et al., Urotensin II differentially regulates macrophage and hepatic cholesterol homeostasis. Peptides. 2011 May;32(5):956-63
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory