About   Help   FAQ
Targeted Allele Detail
Symbol: Cpeb4tm1.1Yshu
Name: cytoplasmic polyadenylation element binding protein 4; targeted mutation 1.1, Yi-Shuian Huang
MGI ID: MGI:5587820
Gene: Cpeb4  Location: Chr11:31872211-31935634 bp, + strand  Genetic Position: Chr11, 18.66 cM
Slight increase in dendritic spine length in Cpeb4tm1.1Yshu/Cpeb4tm1.1Yshu neurons

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:209837
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3 loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2 and the selection cassette. Western blot analysis confirmed the absence of protein expression in the brain. (J:209837)
Generation of the Cpeb4tm1.1Yshu allele
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cpeb4 Mutation:  3 strains or lines available
Original:  J:209837 Tsai LY, et al., CPEB4 knockout mice exhibit normal hippocampus-related synaptic plasticity and memory. PLoS One. 2013;8(12):e84978
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory