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Sucla2Gt(SAbetageo)1Bhg
Gene trapped Allele Detail
Nomenclature
Symbol: Sucla2Gt(SAbetageo)1Bhg
Name: succinate-Coenzyme A ligase, ADP-forming, beta subunit; gene trap 1, Brett H Graham
MGI ID: MGI:5585619
Synonyms: Sucla2SAbeta-geo
Gene: Sucla2  Location: Chr14:73552786-73596144 bp, + strand  Genetic Position: Chr14, 39.06 cM, cytoband D2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213453
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Gene trapped (Hypomorph, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsThe beta-geo containing gene trap inserted into intron 4. RT-PCR confirmed low level expression of the wild-type transcript. (J:213453)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sucla2 Mutation:  12 strains or lines available
References
Original:  J:213453 Donti TR, et al., Screen for abnormal mitochondrial phenotypes in mouse embryonic stem cells identifies a model for succinyl-CoA ligase deficiency and mtDNA depletion. Dis Model Mech. 2014 Feb;7(2):271-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory