Erg^tm1.1Sho
Targeted Allele Detail

Summary

• Symbol: Erg^tm1.1Sho
• Name: ETS transcription factor; targeted mutation 1.1, Stuart Orkin
• MGI ID: MGI:5578611
• Synonyms: Erg-GFP-L-S-L
• Gene: Erg Location: Chr16:95160028-95387452 bp, - strand Genetic Position: Chr16, 56.04 cM
• Alliance: Erg^tm1.1Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:212219
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced into intron 1, an GFP reporter, floxed neomycin resistance cassette, stopper cassette and loxP site. Cre-mediated recombination removed the selection and stopper cassettes. (J:212219)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Erg Mutation: 27 strains or lines available

References

• Original: J:212219 Baena E, et al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes Dev. 2013 Mar 15;27(6):683-98
• All: 1 reference(s)