Tg(CAG-Ubqln1)2Hmw
Transgene Detail

Summary

• Symbol: Tg(CAG-Ubqln1)2Hmw
• Name: transgene insertion 2, Hongmin Wang
• MGI ID: MGI:5576803
• Transgene: Tg(CAG-Ubqln1)2Hmw Location: unknown
• Alliance: Tg(CAG-Ubqln1)2Hmw page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Ubqln1)2Hmw expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ubqln1 (MGI:1860276)

• Mutation details: The transgene expresses a full-length mouse Ubqln1 cDNA under the control of the CMV enhancer/chicken beta-actin promoter. Immunoblot analysis indicates striking overexpression in the brain, heart, liver and skeletal muscle with lower levels of overexpression seen in other tissues. (J:206930)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:206930 Liu Y, et al., Ubiquilin-1 protects cells from oxidative stress and ischemic stroke caused tissue injury in mice. J Neurosci. 2014 Feb 19;34(8):2813-21
• All: 3 reference(s)