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Ppardtm1(PPARD)Bsls
Targeted Allele Detail
Nomenclature
Symbol: Ppardtm1(PPARD)Bsls
Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Bart Staels
MGI ID: MGI:5576390
Synonyms: PpardeltaKI
Gene: Ppard  Location: Chr17:28232754-28301469 bp, + strand  Genetic Position: Chr17, 14.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211453
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin resistance cassette and the human cDNA replaced the coding sequence of exons 3 through 8. (J:211453)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ppard Mutation:  60 strains or lines available
References
Original:  J:211453 Gross B, et al., Generation and characterization of a humanized PPARdelta mouse model. Br J Pharmacol. 2011 Sep;164(1):192-208
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory