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Sod1m1H
Chemically induced Allele Detail
Nomenclature
Symbol: Sod1m1H
Name: superoxide dismutase 1, soluble; mutation 1, Harwell
MGI ID: MGI:5575771
Synonyms: Sod1D83G
Gene: Sod1  Location: Chr16:90220762-90226333 bp, + strand  Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced an A to G transition in exon 3 that results in an aspartic acid to glycine missense mutation (D83G). Dismutase activity of the mutant protein is severely reduced compared to the wild-type protein. (J:169366, J:219360)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sod1 Mutation:  15 strains or lines available
References
Original:  J:169366 MouseBookTM, Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory