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Gt(ROSA)26Sortm1(CAG-Bcl3,-EGFP)Hoev
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm1(CAG-Bcl3,-EGFP)Hoev
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nadine Hovelmeyer
MGI ID: MGI:5574111
Synonyms: Bcl-3Ind
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077244 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:208980
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(CAG-Bcl3,-EGFP)Hoev expresses 1 gene
 
Mutation detailsThe targeting construct introduced into the locus a CAG promoter, floxed neomycin resistance/STOP cassette, Bcl3 coding sequence and FRT-flanked IRES-EGFP. (J:208980)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  512 strains or lines available
References
Original:  J:208980 Hovelmeyer N, et al., Overexpression of Bcl-3 inhibits the development of marginal zone B cells. Eur J Immunol. 2014 Feb;44(2):545-52
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory